Details, Fiction and megatomi.com
Details, Fiction and megatomi.com
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Our new Apparent+ tissue clearing procedure is the sole process that delipidates samples without adjust in morphology and with negligible influence on structural integrity.
Megatome is a vibrating microtome designed to area a broad number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome allows high-throughput tissue sectioning with uniform area profile, and also minimal tissue destruction and knowledge reduction.
Antibodies might acquire weeks to diffuse by only a few millimeters of tissue, by using a steep labeling gradient from surface to core.
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SE employs a rotational electric powered field to disperse very electromobile molecules (for instance antibodies or surfactant micelles) throughout a porous sample with out detrimental electrically billed buildings in the tissue. This enables 2-4 day clearing of intact organs,
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Megatome is really a novel microtome that allows for top-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue harm and knowledge decline.
It’s time to up grade your microtome to Megatome. With correct higher-frequency slicing for an unmatched number of sample measurements and kinds – from organoids and tumors megatomi.com to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied programs.
Thoroughly delipidate entire mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing kit.
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Defend avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, guarding specimens for a number of rounds of processing.
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Our novel SHIELD tissue preservation technique forms intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.